The following are summaries related to new research on various COPD studies and reports.
New Treatment to Combat COPD
A new report published in The FASEB Journal discusses a new drug to fight off the effects of COPD.
The study examined the effectiveness of a receptor type medication which researchers believe could reverse the inflammatory response of COPD by blocking a molecule risk factor.
Researchers found by impeding RAGE (receptor for advanced glycan end products), inflammatory responses up to 20% can reduce COPD flares, and there was reduced airway damage in mice. RAGE has been identified as a risk gene for COPD development.
Juvenile Fibromyalgia: What You Need to Know
Fibromyalgia is a condition characterized by widespread musculoskeletal pain, fatigue, sleep issues, and mood problems. Research shows that fibromyalgia is the result of amplified pain signals in the brain.
Fibromyalgia is often seen as a condition only affecting adults, but it also affects young children and teenagers. There are few studies in the United States about the number of adolescents living with fibromyalgia, but some estimates are as high as 6%, this according to the National Fibromyalgia & Chronic Pain Association (NFMCPA).
If your child has been diagnosed with juvenile fibromyalgia (JFM), here is what you need to know.
One report published in Nature Reviews Rheumatology notes at least 25% of school aged children live with chronic pain and some of them report widespread chronic pain.
Unfortunately, there is insufficient current research on proper identification of juvenile fibromyalgia and doctors must rely on guidelines established in 1985 by the American College of Rheumatology (ACR) for diagnosing juvenile fibromyalgia.
Fibromyalgia is more common in girls than boys, and mostly diagnosed between the ages of 13 to 15.
In rheumatology practices, fibromyalgia is fairly common and according to Dr. Susmita Kashikar-Zuck of Cincinnati Children’s Hospital Medical Center in Ohio, her practice is seeing 40 to 45 new cases of juvenile fibromyalgia per year.
Chronic widespread all over body pain is the main symptom of fibromyalgia and is experienced by both children and adults. Fibromyalgia also causes sore spots on the muscles called “tender points,” which hurt when pressure is applied.
Homocystinuria is a genetic disease that is passed on in an autosomal recessive manner. This process means two copies of an irregular gene must be present for a disease to develop.
In this article, we examine what homocystinuria is, what causes it, and what symptoms it produces. We also look at diagnosis and treatment of the disease.
What is homocystinuria?
In homocystinuria, the body is unable to breakdown certain proteins. Specifically, the condition affects an amino acid called methionine.
Amino acids are essential human building blocks. Methionine is a naturally occurring protein that babies need for growth and adults need for regulating nitrogen in the body. All amino acids contain nitrogen, making nitrogen an important part of human DNA.
There are several different forms of homocystinuria, which are set apart by their symptoms.
The most common form is called cystathionine beta-synthase (CBS). CBS differs from other types of homocystinuria because it causes the following symptoms:
- dislocation of the front eye lenses
- increased blood clotting
- brittle bones or other skeletal abnormalities
CBS can also cause developmental delays and learning disabilities.
Other less common forms of homocystinuria may cause a variety of other symptoms.
Understanding the Complications of Liver Cancer
Receiving a liver cancer diagnosis can be frightening, and you probably have many questions. Perhaps, there is one you are afraid to ask.
You want to know if liver cancer is fatal and how much time do you have left. Both are questions that don’t have exact answers, but your likely outcome will depend on how advanced your cancer is.
Are You Ready?
The information on liver cancer survival rates may be difficult to process and is not something you should read up on if you are not ready for this information.
An important thing to consider is the survival statistics for liver cancer are general and do not necessarily apply to your unique case. No two cases are exactly alike, and the response to treatment varies from person to person.
Lastly, no one can tell you how long you will live with liver cancer or if you will be cured.
The decision to talk to your doctor about your prognosis is personal, and it is up to you to decide how much you want to know. Some people feel that it makes it easier to cope if they know what they are up against and others find survival statistics to be scary and confusing.
Your cancer doctor is the most familiar with your health and can discuss your prognosis and explain what the statistics mean for you. It is important to note and understand that your prognosis can change and cancer treatment outcomes are hard to forecast with precise accuracy.
Read the rest at New Life Outlook.
Depression is one of the most common mental health issues in the United States.
According to the Centers for Disease Control and Prevention (CDC), depression affects 1 in 20 Americans over the age of 12, and the World Health Organization (WHO) reports depression affects more than 300 million people worldwide.
Despite the prevalence of depression in the United States and around the world, depression is a very misunderstood condition. It’s no surprise that people who are living with depression get frustrated by the lack of knowledge and understanding from others when explaining their condition.
9 Things Depressed People Want You to Know
I have struggled with depression for most my adult life and I’ve tried to explain my struggle with depression to others, but these conversations didn’t go as well as I wanted.
It felt like my friends and family didn’t understand what depression is and how it affects people.
If I could speak up for others living with depression, here are some of the things I think they would want their friends and loved ones to know about the condition.
Anyone Can Suffer From Depression
Depression doesn’t have a stereotype and it doesn’t discriminate. It can affect anyone at any age, gender, race or ethnic group.
Depression is the result of chemical imbalances in the brain, hormonal changes, or stress from the things that are going in your life.
Depression Does Not Equal Weakness
Many people think being depressed means you are weak and that is not true. The strongest people are the ones who find themselves depressed.
I am the strongest person that most people know, and I’m the one that everyone relies on. This had me thinking about how I have to bear the most and ask for little help.
Pain is a big problem for people with kidney cancer, especially if the cancer is an advanced stage and has spread to nearby organs or the bones.
Up to 80% of advanced cancer patients experience pain, according to one report from the Cleveland Clinic.
Another study published in The International Journal of Psychiatry in Medicine finds up to 50% of people continue to experience pain, resulting in functional limitations, even years after cancer treatment has ended.
Cancer pain and post-cancer pain can be moderate to severe and affect your ability to participate in daily activities and your overall quality of life.
Sources of Kidney Cancer Pain
If you experience pain on one side of the body between the upper abdomen and back, this is called “flank pain,” coming from your kidney, likely from a tumor pressing on the organ. You may also experience pain if the tumor has grown and is pressing on nearby organs or nerves.
Pain is one of the many side effects of cancer treatments. Radiation therapy may cause burning sensations or painful scars, and chemotherapy has been known for causing mouth sores and nerve damage.
Postoperative pain, if you have had surgery to remove tumors or a kidney, can also compromise your life quality.
If your kidney cancer has spread to your bones, it is called bone metastasis. This condition may cause excruciating pain and may even cause your bones to break.
About one-third of people with kidney cancer eventually develop bone metastasis, according to one 2016 report from the International Journal of Molecular Studies.
Latest Dementia and Alzheimer’s Research News
The following are summaries related to new research on various dementia and Alzheimer’s disease studies and reports.
Proton Pump Inhibitors Do Not Cause Alzheimer’s or Dementia
A new study published in the Journal of the American Geriatrics Society looked at the safety of Proton Pump Inhibitors (PPIs) and any risks they may pose for dementia, mild cognitive impairment, or Alzheimer’s disease.
Previous reports have indicated a link between PPIs – medications used to manage ulcers and reflux disease – and the increased risk of Alzheimer’s and dementia.
The researchers looked at data from the National Alzheimer’s Coordinating Center (NACC) database from 2005 to 2015. The information came from people who are 50 and older who had either normal brain function or mild cognitive impairment, and the researchers noted their use of PPIs.
Of the 10,000 participants:
- 73% never used PPIs
- 18% used them occasionally
- 8% were using them often
The people taking PPIs were also using medications for treating sleep disorders, incontinence, and depression. All of these medications are known to be linked to cognitive impairment.
Interestingly, there was decreased risk of cognitive decline in the patients taking PPIs and the researchers indicated further investigation was needed to explain the decline.
Research Shows Gaps in Healthcare in Alzheimer’s Patients Who Live Alone
A report in the Journal of Alzheimer’s Disease found that 46% of people with Alzheimer’s in Sweden live alone and are primarily older women.
Proposing the idea that Alzheimer’s patients who are living alone may not be receiving the same adequate health care and treatment as those who live someone.
COPD and Smoking: How Are The Two Related?
Smoking is one of the causes of chronic obstructive pulmonary disease (COPD.)
Smoking damages airways, air sacs, and the lining of your lungs. Damaged lungs cannot do their job of moving air in and out – making it hard to breathe.
COPD has become the third death leading cause of death in the United States, this according to data from the National Center for Health Statistics, a division of the American Centers for Disease Control (CDC).
The National Institutes of Health (NIH) reported that at least 12 million adults have been diagnosed with COPD. It is also believed that another 12 million are undiagnosed.
The NIH further reports that 120,000 people die each year from COPD complications. It appears more women are dying from COPD than men, and these numbers have increased in recent years.
Doctors recognize the role that tobacco use plays in the development of COPD but getting people to quit smoking isn’t easy. The good news is that smoking cessation programs have gotten better and smokers can benefit from a variety of treatment methods.
COPD and Smoking Statistics
According to the International Journal of Environmental Research and Public Health, there have been at least one hundred million deaths in the 20th century related to smoking. That number is predicted to be one billion for tobacco use in the 21st century.
Lifelong smokers have a 50% chance of developing of COPD and breathing in second-hand smoke can increase your chances of developing COPD.
Accidental poisoning by soap products occurs when a person comes in contact with soap products that contain strong chemicals. Contact often takes place through the eyes or mouth.
Products that can cause soap poisoning range from simple soaps to products containing a chemical called amine oxide. If these products are inhaled or swallowed, they can be highly toxic and even fatal.
If someone suspects that a person has been exposed to harmful chemicals and poisoned, they should call emergency medical services immediately or call their country’s National Poison Control Center (NPCC) as soon as possible. In the United States, the number to call is 1-800-222-1222.
The Latest News About Liver Cancer Research
The following are summaries related to new research on various liver cancer studies.
Coffee Might Keep Liver Cancer Away
New research shows drinking coffee may reduce your risk of developing liver cancer. The study comes from researchers out of the University of Southampton and the University of Edinburgh.
Published in the medical journal BMJ Open, the study finds people who drink coffee — both caffeinated and decaffeinated — are less likely to develop the most common type of liver cancer, hepatocellular cancer (HCC.) This type of liver cancer occurs mostly in people who have liver disease, specifically hepatitis B or C.
The UK researchers found the more coffee you consume, the greater protection you have against HCC. One daily cup of coffee reduces the risk of developing HCC by 20% and two cups more added up to a 35% percent risk reduction.
Drinking up to five cups could cut your risk in half. However, there was no further data on consuming more than five cups daily.